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"Understanding CML 100 100 answers the door" is a book containing the questions and answers for chronic myeloid leukemia. 15 people have about what is chronic myeloid ideal standard leukemia in chronic myeloid leukemia, early diagnosis and test methods, initial treatment, follow-up of the course of treatment, side effects, and the 23-line treatment of chronic myeloid leukemia, allogeneic HSCT, and other more the contents carefully itemized and explained to wonder ideal standard at eye level for easy understanding for the reader.
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Author: jeongjuseop Professor of Internal Medicine, Pusan National University Hospital Oncology
Is 001 normal ideal standard blood overview of Part 1 consists of chronic myelogenous leukemia, how? Is the role of 002 leukocytes What specifically? 003 In what kind of leukemia, and myeloid is whether a certain sense, is the difference between acute and chronic are non-Oh! For a 004 increase in the symptoms of chronic leukemia is what leukocytes ideal standard and platelets, have an infection or anemia ideal standard may be accompanied? ideal standard 005 In the case of chronic leukemia What is the function of the spleen, ideal standard the spleen can grow to that? Is 006 Chronic myelogenous leukemia is genetic? 007 leukemia survival rate, disease-free survival, What is the meaning of the leukemia-related deaths? 008 Is it possible to treat chronic ideal standard myelogenous leukemia in outpatient? Is the early symptoms of early symptoms ideal standard and diagnosis of chronic myeloid leukemia and inspection 009 Part 2, chronic myelogenous leukemia, what? 010 primary clinics and screening agencies to question the CML happens when the power to request any findings by the University Hospital? 011 I receive some tests to confirm the diagnosis of chronic myeloid leukemia at the University Hospital? Do I have a bone marrow biopsy for the diagnosis of chronic myelogenous leukemia (AML) 012? How will progress bone marrow is there any side effects? ideal standard 013 What is a chromosome, the Philadelphia chromosome, bcr-abl fusion ideal standard gene What? 014 What is molecular biology ideal standard called PCR test to test, to make sure I do? 015 chronic myeloid leukemia called Philadelphia chromosome negative diagnosis has been - is called atypical forms. Is the treatment different? 016 What is a tyrosine kinase that, why is it important? 017 found in the peripheral blood as the Philadelphia chromosome found through bone marrow biopsy is there any difference? What is 018 fluorescent chromosome test? 019 Diagnosis of treatment is to be good, or What prognostic factors to predict whether aneulji? ideal standard 020 chronic phase, acceleration, What are the acute phase of the diagnostic criteria?
Part 3 The first treatment Imagination tinip 021 (Gleevec ) The treatment plan and outcome of chronic myeloid leukemia before development of chronic myelogenous leukemia did like? Imagination tinip 022 (Gleevec ) is used for a long time I hear about What is Therapy? What is the 023 tyrosine kinase inhibitors? Imagination tinip 024 (Gleevec ) I know that many drugs are available in addition to the initial treatment of choice, I choose a PCP drug, taking into account any factors? 025 How do I compare scores ideal standard Imagination as an initial therapeutic tinip (Gleevec ) for nilotinib (other Signa )? What is the comparative scores ideal standard of 026 as the initial therapeutic Imagination tinip (Gleevec ) for dasatinib (SPRYCEL )? Even tinip 027 (Shu defect ) is possible and to prescribe the drug itself with some patients developed in our country, efficacy and safety are what go? Is there a treatment plan to go to a big hospital that around 028 depending on the hospital? 029 chronic phase, accelerators, is the initial treatment plan is different, depending on the acute phase? May I 030 doctor to invite to participate in clinical research? 031 Is this another way of taking each drug? If you should take your medicine at the same time every day, eat out once doeneunjiyo? 032 Do I need a treatment, such as age, young people, even though more than 75 years? Imagination tinip 033 (Gleevec ), nilotinib (other Signa ), What is the drug that should not be taken with tyrosine kinase inhibitors such as dasatinib (SPRYCEL ) is? The initial therapeutic dose of 034 tinip Imagination (Gleevec )? Side effects and how can I stop loss or take over when the examination? The initial therapeutic dose of 035 nilotinib (other Signa )? About the side effects and laboratory capacity ideal standard when reducing or taking on more than you can stop in any case, what do I do? 036 The initial therapeutic dose of dasatinib (SPRYCEL )? Side effects and how can I stop loss or take over when the examination? 037 to take the medicine well after treatment started, it is very important. What is medication fidelity important? Is it possible careers and daily lives of 038 medication? ideal standard 039 Is there a food to be avoided by all means of tyrosine kinase inhibitor ideal standard dose?
I started to follow up Part 4 040 treatment courses of treatment of chronic myeloid leukemia and exotic How often should I visit? 041 treatment goal of hematologic, cytogenetic, molecular biological What is the reaction? 042 When the healing process of the bone marrow, which happens to be the same? Do I need on a regular basis? Molecular genetic testing of the 043 biological treatment process inspection and when it happens in any event? ideal standard Why do you often? The genetic test genetic material from 044 to diminish the increase was again a major molecular biological reaction chamber What does this mean? What is the meaning of 'appropriate response' of the 045 treatment? 046 What is the meaning of 'warning' treatment, what should I do? 047 What is the meaning of "inadequate response" of the treatment, what should I do? What is IS in the 048 PCR test? 049 doctors are getting better as I believe that this bottle what basis? After eating about 050 regular blood tests are normal and should I just can not get my symptoms expensive test? Is 051 being the most complete treatment status is unknown for some test results? Is 052 treatment after the initial response level of the main factors influencing the next three months treatment outcome? What will other chromosomal abnormalities have emerged in addition to the 053 Philadelphia chromosome karyotyping? 054 What's the difference between the initial treatment after primary resistance and secondary resistance ideal standard is, What does this mean? 055 Anything can break a bottle of medicine to jyeotdago like? If the 056 patients in the chronic phase of the study was the effect is good to watch after drug interruption, if any, and to try to stop, I have seen some test after being stopped? 057 treatment of chronic myeloid leukemia ideal standard are aware that by adjusting the figures through chemotherapy. If not get the full molecular biological reactions, while maintaining a certain degree of PCR figures Can I live without any problem to health? Is there a case came about 058 full molecular biological patient does not come about or hematologic remission in some cases, cytogenetic?
What kinds of major adverse side effects of tyrosine kinase inhibitors 059 Part 5 tinip Imagination (Gleevec ideal standard ) have? What are the major side effects of nilotinib 060 (other Signa )? The 061 has a major side effect of dasatinib (SPRYCEL ) What are? How jimyeo rating of 062 numbered side effects, what is its significance? If the blood is reduced side effects caused 063 saenggimyeo any symptoms, how do you measure is? 064 nilotinib (other Signa ) Will I need any tests to confirm the adverse effects of taking even if no symptoms? 065 dasatinib (SPRYCEL ) Will I need any tests to verify the reaction of taking over? 066 vascular ideal standard side effects of nilotinib (other Signa ) is called the rare important and dangerous adverse reactions. What is the expected symptoms, can I check through any tests? Pulmonary vascular ideal standard side effects of 067 dasatinib ideal standard (SPRYCEL ) is called the rare important and dangerous adverse reactions. What is the expected symptoms, can I check through any tests? If you are taking medications of 068 tyrosine kinase inhibitors have been temporarily suspended, the next step of repeat doses can I work? 069 to tyrosine kinase inhibitor medication if you get along after 1-2 years without any side effects Can be side effects caused new?
Part 6 2-line treatment of chronic myeloid leukemia in chronic phase of treatment Accelerator ideal standard 070, I heard that the transition to the acute phase. New saenggimyeo any symptoms, the diagnosis of any possible inspection ideal standard findings? 071 and Imagination tinip (Gleevec ) the tolerance is what it means to have occurred from eating, do you know by any test? 072 What is the treatment of genetic ideal standard mutations, what should I do saenggimyeon of mutants resistant or treatment? 073 does my drug choice depends on the mutation? Is 074 T315I mutation is why is it important? Is Imagination tinip 075 (Gleevec ) if the refractory or fire tolerability of the treatment is any treatment? 076 nilotinib (other Signa ) or dasatinib (SPRYCEL ) If you look for refractory or non-clinical tolerability of the treatment there any treatment? 077 doses of the drug in the bone marrow and peripheral blood comes on, but the Philadelphia chromosome is still scan is normal, can not I eat for no side effects of the medicine continue the same medicine? What are the reasons and mechanisms caused ideal standard tyrosine kinase inhibitor drug resistance in 078? Imagination tinip 079 (Gleevec ) and is taking nilotinib ideal standard (other ideal standard Signa ) or if you are taking dasatinib (SPRYCEL ) a secondary ideal standard drug Glivec case to be taken back adverse health insured Will? 080 PCR levels continue to decrease, although the doctor hears no good reason (such as myelodysplastic syndrome Merger) What is? <